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Marc C Hochberg Selected Research

fibroblast growth factor 18

1/2021Long-term structural and symptomatic effects of intra-articular sprifermin in patients with knee osteoarthritis: 5-year results from the FORWARD study.
1/2020Intra-articular sprifermin reduces cartilage loss in addition to increasing cartilage gain independent of location in the femorotibial joint: post-hoc analysis of a randomised, placebo-controlled phase II clinical trial.
10/2019Effect of Intra-Articular Sprifermin vs Placebo on Femorotibial Joint Cartilage Thickness in Patients With Osteoarthritis: The FORWARD Randomized Clinical Trial.

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Marc C Hochberg Research Topics

Disease

39Osteoarthritis
05/2021 - 01/2002
28Pain (Aches)
10/2022 - 01/2002
21Rheumatoid Arthritis
05/2021 - 01/2002
19Knee Osteoarthritis
01/2021 - 05/2004
12Osteoporosis
12/2013 - 04/2002
8Osteoporotic Fractures
08/2012 - 12/2003
6Arthritis (Polyarthritis)
12/2013 - 01/2002
5Inflammation (Inflammations)
12/2020 - 01/2002
5Bone Resorption
01/2018 - 10/2004
4Infections
01/2022 - 03/2008
4Necrosis
01/2018 - 04/2011
3Weight Loss (Weight Reduction)
01/2021 - 01/2020
3Overweight
01/2020 - 01/2013
3Hip Fractures (Intertrochanteric Fractures)
01/2018 - 05/2005
3Osteophyte
01/2017 - 12/2003
3Neoplasms (Cancer)
08/2015 - 06/2013
3Wrist Fractures
05/2012 - 10/2004
3Ulcer
12/2011 - 01/2002
2Arthralgia (Joint Pain)
10/2019 - 01/2013
2Chronic Pain
02/2016 - 11/2002
2Ankylosing Spondylitis
12/2013 - 09/2002
2Hypertension (High Blood Pressure)
05/2010 - 05/2007
2Macular Degeneration (Age-Related Maculopathy)
09/2008 - 05/2008
2Postmenopausal Osteoporosis
05/2005 - 01/2005
2Hip Osteoarthritis (Coxarthrosis)
01/2005 - 12/2003
2Myocardial Infarction
08/2004 - 01/2003
1COVID-19
01/2022
1Vitamin D Deficiency
01/2019
1Obesity
01/2019
1Disease Progression
10/2018
1Psoriatic Arthritis
01/2018
1Stress Fractures (Stress Fracture)
02/2016
1Cancer Pain
02/2016
1Osteonecrosis (Kienbock's Disease)
02/2016
1Low Back Pain (Lumbago)
02/2016
1Postoperative Pain
10/2014
1Acute Pain
10/2014
1Diarrhea
09/2014
1Headache (Headaches)
09/2014

Drug/Important Bio-Agent (IBA)

13Non-Steroidal Anti-Inflammatory Agents (NSAIDs)IBA
01/2021 - 01/2002
11Biological ProductsIBA
08/2015 - 12/2007
10Antirheumatic Agents (DMARD)IBA
01/2021 - 12/2007
8Biomarkers (Surrogate Marker)IBA
10/2018 - 03/2003
7Naproxen (Naprosyn)FDA LinkGeneric
12/2011 - 12/2002
6Pharmaceutical PreparationsIBA
01/2021 - 05/2008
6Abatacept (Orencia)FDA Link
01/2018 - 01/2010
6Glucosamine (Dona)IBA
02/2016 - 11/2010
5GlucocorticoidsIBA
01/2020 - 11/2003
5Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
01/2018 - 06/2005
5Chondroitin Sulfates (Chondroitin Sulfate)IBA
02/2016 - 11/2008
5Celecoxib (Celebrex)FDA Link
01/2016 - 12/2002
5Alendronate (Alendronate Sodium)FDA LinkGeneric
08/2012 - 01/2005
5Prostaglandin-Endoperoxide Synthases (Cyclooxygenase)IBA
08/2004 - 01/2002
4Analgesics (Analgesic Drugs)IBA
01/2021 - 01/2013
4Cyclooxygenase 2 Inhibitors (COX-2 Inhibitors)IBA
08/2004 - 01/2002
3Vitamin DFDA LinkGeneric
05/2021 - 08/2003
3fibroblast growth factor 18IBA
01/2021 - 10/2019
3hydroxide ionIBA
01/2019 - 12/2010
3Tumor Necrosis Factor InhibitorsIBA
02/2014 - 06/2005
3Interleukin-6 (Interleukin 6)IBA
12/2013 - 10/2004
3Diphosphonates (Bisphosphonates)IBA
01/2012 - 01/2005
3Ibuprofen (Motrin)FDA LinkGeneric
08/2004 - 12/2002
3Aspirin (Acetylsalicylic Acid)FDA LinkGeneric
08/2004 - 12/2002
2tanezumabIBA
01/2021 - 02/2016
2Methotrexate (Mexate)FDA LinkGeneric
01/2021 - 02/2014
2Clk dual-specificity kinasesIBA
12/2020 - 10/2020
2lorecivivintIBA
12/2020 - 10/2020
2Brain-Derived Neurotrophic Factor (BDNF)IBA
08/2019 - 01/2016
2Nerve Growth Factor (NGF)IBA
02/2016 - 05/2013
2Monoclonal AntibodiesIBA
02/2016 - 05/2013
2Diclofenac (SR 38)FDA LinkGeneric
06/2015 - 09/2014
225-hydroxyvitamin DIBA
12/2014 - 12/2010
2Calcitriol Receptors (Calcitriol Receptor)IBA
12/2013 - 05/2007
2Duloxetine Hydrochloride (Cymbalta)FDA Link
05/2013 - 02/2012
2Carotenoids (Carotene)IBA
10/2012 - 10/2012
2Estrogens (Estrogen)FDA Link
05/2012 - 10/2004
2Esomeprazole (Nexium)FDA Link
12/2011 - 06/2011
2Hormones (Hormone)IBA
09/2008 - 05/2007
2Adrenal Cortex Hormones (Corticosteroids)IBA
12/2007 - 05/2007
2CalciumIBA
05/2007 - 08/2003
2rofecoxib (Vioxx)FDA Link
01/2005 - 12/2002
2lumiracoxib (prexige)IBA
08/2004 - 08/2004
1Tyrosine (L-Tyrosine)FDA Link
12/2020
1Phosphotransferases (Kinase)IBA
12/2020
1Dyrk KinasesIBA
10/2020
1Dihydrotachysterol (AT 10)IBA
10/2019
1cyclo(Arg-Pro) (CI 4)IBA
10/2019
1Indomethacin (Indometacin)FDA LinkGeneric
10/2014

Therapy/Procedure

17Therapeutics
01/2021 - 01/2002
6Replacement Arthroplasty
01/2022 - 12/2005
3Tai Ji (Tai Chi Chuan)
01/2020 - 04/2012
3Ambulatory Care (Outpatient Care)
02/2010 - 12/2003
2Intra-Articular Injections
01/2021 - 05/2013
2Canes (Cane)
01/2020 - 01/2020
2Injections
01/2020 - 01/2020
2Orthotic Devices (Orthosis)
01/2020 - 01/2020
2Hip Replacement Arthroplasty (Total Hip Replacement)
05/2004 - 12/2003
1Walkers
10/2022
1Inappropriate Prescribing
05/2021
1Activities of Daily Living (ADL)
08/2019